張天豪 助理教授

職稱

助理教授

電話

+886-6-275-7575 ext. 62421

傳真

+886-6-234-5482

電子信箱

darby@ee.ncku.edu.tw

實驗室

分子生醫實驗室（台南市大學路1號 電機系館92691室）

開授課程

98學年度第一學期

·         機器學習與生物資訊學

97學年度第二學期

·         數值分析

97學年度第一學期

·         機器學習與生物資訊學

96學年度第二學期

·         機器學習與生物資訊學

96學年度第一學期

·         電與生活

·         數值分析

　

學歷
  • 國立臺灣大學資訊工程博士(2006) Ph.D., National Taiwan University, Taiwan
  • 國立臺灣大學資訊工程碩士(2004) M.S., National Taiwan University, Taiwan
  • 國立臺灣大學資訊工程學士(2002) B.S., National Taiwan University, Taiwan
                                                                                                                  

經歷
  • 成功大學電機系助理教授(2006/8~ )
    　

專長及研究領域
  • 生物資訊與計算生物學
  • 機器學習
    　

榮譽及獎勵 (至少五年內)

 

專利 (至少五年內)

 

著作 (至少五年內)

A.   Journal Papers

1. Darby Tien-Hao Chang, Ting-Ying Chien and Chien-Yu Chen, "seeMotif: exploring and visualizing sequence motifs in 3D structures", Source: NUCLEIC ACIDS RESEARCH    Volume: 37    Pages: W552-W558    Supplement: Suppl. S    Published: JUL 1 2009  

 

2. Darby Tien-Hao Chang, Chih-Ching Wang and Jian-Wei Chen, "Using a kernel density estimation based classifier to predict species-specific microRNA precursors", Source: BMC BIOINFORMATICS    Volume: 9  Article Number: S2    Supplement: Suppl. 12    Published: 2008  

   

3. Darby Tien-Hao Chang, Hsuan-Yu Huang, Yu-Tang Syu and Chih-Peng Wu, "Real value prediction of protein solvent accessibility using enhanced PSSM features", BMC BIOINFORMATICS    Volume: 9  Article Number: S12    Supplement: Suppl. 12    Published: 2008.

 

4.Ting-Ying Chien, Darby Tien-Hao Chang, Chien-Yu Chen, Yi-Zhong Weng and Chen-Ming Hsu, "E1DS: catalytic site prediction based on 1D signatures of concurrent conservation", Nucleic Acids Research, Vol. 36, Web Server Issue, W291-W296, 2008. (SCI)
　

      5.Darby Tien-Hao Chang, Yu-Yen Ou, Hao-Geng Hung, Meng-Han Yang, Chien-Yu Chen and Yen-Jen Oyang, "Prediction of protein secondary structures with a novel kernel density estimation based classifier", BMC Research Notes, 1:51, 2008.

6. Darby Tien-Hao Chang, Yi-Zhong Weng, Jung-Hsin Lin, Ming-Jing Hwang, and Yen-Jen Oyang, "Protemot: prediction of protein binding  sites with    automatically extracted geometrical templates", to appear  in the 2006 Web Server Issue of Nucleic Acids Research. (SCI)
　

      7. Darby Tien-Hau Chang, Yen-Jen Oyang, and Jung-Hsin Lin, "MEDock: a Web Server for Efficient Prediction of Ligand Binding Sites Based on a Novel Optimization Algorithm", Nucleic Acids Research, Vol. 33, Web Server Issue, W233-W238, 2005. (SCI)
　

      8. Darby Tien-Hau Chang, Chien-Yu Chen, Wen-Chin Chung, Yen-Jen Oyang, Hsueh-Fen Juan, and Hsuan-Cheng Huang, "ProteMiner-SSM: A Web Server for Identifying Possible Protein-Ligand Interactions Based on Analysis of Protein Tertiary Substructures", Nucleic Acid Research, Vol. 32, 2004. (SCI)

 

B. Conference papers

   1.Ting-Ying Chien, Darby Tien-Hao Chang, Chien-Yu Chen, Yi-Zhong Weng, and Chen-Ming Hsu, "E1DS: catalytic site prediction based on 1-dimensional signatures of concurrent conservation", in Poster Proceedings of the 16th Annual International Conference Intelligent Systems for Molecular Biology, Toronto, Canada, 2008. (ISMB 2008)
 
2.Yen-Jen Oyang, Darby Tien-Hao Chang, Yu-Yen Ou, Hao-Geng Hung, and Chien-Yu Chen, "Prediction of Protein Secondary Structures with a Novel Kernel Density Estimator", in Proceedings of the 2007 International Conference on Machine Learning: Models, Technologies & Applications, 2007. (MLMTA 2007)

3.Ting-Ying Chien, Chien-Yu Chen, Darby Tien-Hao Chang, and Chen-Ming Hsu, "Deriving Functional Signatures from Protein Sequences by Iterative Pattern Mining", in Proceedings of the Eleventh Annual International Conference of Research in Computational Molecular Biology, San Francisco Bay Area, 2007. (RECOMB 2007)

4. Yen-Jen Oyang, Darby Tien-Hau Chang, Yu-Yien Ou, Shien-Ching Hwang, and Chien-Yu Chen, "On the Convergence Rates of the Locally  Relaxed Kernel Density Estimator, in Proceedings of the 2006 Hawaii International Conference on Statistics, Mathematics and Related Fields, 2006.
　

      5. Yen-Jen Oyang, Yu-Yien Ou, Shien-Ching Hwang, Chien-Yu Chen, and Darby Tien-Hau Chang, "The Locally Relaxed Model of Variable Kernel Density Estimation", in Proceedings of the 2006 Hawaii International Conference on Statistics, Mathematics and Related Fields, 2006.
　

      6. Yen-Jen Oyang, Yu-Yien Ou, Shien-Ching Hwang, Chien-Yu Chen, and Darby Tien-Hau Chang, "Data Classification with a Relaxed Model of Kernel Density Estimation", in Proceedings of the 2005 International Joint Conference on Neural Networks, 2005.
　

      7. Darby Tien-Hau Chang, Chien-Yu Chen, Yen-Jen Oyang, Hsueh-Fen Juan, Hsuan-Cheng Huang, "An Efficient Mechanism for Prediction of Protein-Ligand Interactions Based on Analysis of Protein Tertiary Substructures", in Proceedings of IEEE Fourth Symposium on Bioinformatics and Bioengineering (BIBE 2004)
　

      8. Yen-Jen Oyang, Darby Tien-Hau Chang, Chien-Yu Chen, and Shien-Ching Hwang, "Expediting Protein Structural Analysis with an Efficient Kernel Density Estimation Algorithm", in Proceedings of IEEE 5th International Symposium on Multimedia Software Engineering, Taichung, Taiwan, 2003.

　

研究計畫 (至少五年內)

A. 國科會計畫

  • 尚無

B. 一般建教案

  • 尚無

指導學生情況 (至少五年內)

A. 指導學生

      碩士班：

        95級：王志清、黃璿宇

        96級：鄭智仁、林義峰、陳建瑋、許育堂

        97級 : 吳建緯、薛正豪、林柏璋、吳季曄

 98級:  黃正一、李建儒、姜知昀

B. 指導學生之特殊榮譽

　

主辦及參與國際會議 (至少五年內)
  • 　

教學與研究國際交流
  • 受聘至國外大學及學術機構講學次數：   次
  • 至國外學術機構訪問次數：    次
  • 指導之學生至國外學術機構訪問人次：      次
  • 指導之學生至國外大學選讀人次：      次
  • 邀請國外教師至本單位訪問人次：     次
  • 邀請國外學生至本單位訪問人次：      次
  • 與國外教師共同主持研究計畫人次：      次